Joe Biden set the stage Wednesday for Barack Obama’s historic address as the Democratic nominee by launching a heated attack tying John McCain to the Bush White House.

On the eve of Hurricane Katrina’s third anniversary, a nervous New Orleans watched Wednesday as another storm threatened to test everything the city has rebuilt.

Hopeful signs for women: Forbes fifth annual ranking showcases women who have beat out men for top posts this year.

Barack Obama became the first African-American ever nominated for president by a major political party after delegates to the Democratic National Convention chose him as their standard-bearer Wednesday.

Iraq is calling on companies to submit designs to build a giant Ferris wheel in Baghdad — the latest in a string of lavish proposals painting the capital as a leisure friendly city.

Union bosses in this region of rural Mississippi have long grumbled that the largest factories here hire illegal immigrants, and that the immigrants were starting to get more overtime and supervisory positions.

A virus designed to swipe passwords from online gamers has inexplicably popped up in some laptop computers aboard the international space station.

A federal jury recommended the death sentence for convicted child killer Joseph Edward Duncan III on charges related to the kidnapping and murder of Dylan Groene.

Law enforcement officers wanted: must work graveyard shifts alone in remote towns along the Mexican border, put in long hours and perform well in triple-digit temperatures.

Joe Biden can be counted on to  make the case for Barack Obama and prosecute the case against John McCain.  But NBC News political director Chuck Todd wonders will he control his instinct to be No. 1?

The brief respite for consumers at the gasoline pump may come to an abrupt end if Tropical Storm Gustav slams into the petroleum-rich Gulf Coast and its numerous refineries, just as Americans begin packing up cars for the Labor Day weekend.

Pioneering lesbian rights activist Del Martin, who married her lifelong partner in June on the first day that same-sex couples here gained that right, has died. She was 87.

The mortgage mess that has upended millions of homeowners’ finances is now taking a bigger bite out of the nation’s banking system.

Gustav swirled toward Cuba on Wednesday after triggering flooding and landslides that killed at least 22 people in the Caribbean. Its track pointed toward the U.S. Gulf coast, including Louisiana.

Western leaders warns Russia to "change course," hoping to keep a conflict that threatens a key nuclear pact and could even raise U.S. chicken prices from blossoming into a new Cold War.

The United States asked Iraq for permission to keep its troops there to 2015, but U.S. and Iraqi negotiators agreed to limit their authorization to 2011, Iraqi President Jalal Talabani said.

For Senator Barack Obama, the theatrics and drama of this one are overwhelming one of his most important tasks here: connecting with the economic anxiety gripping voters and convincing them that he has concrete and achievable solutions.

Indian officials rushed soldiers and air force helicopters Wednesday to flood-ravaged parts of northern India to provide aid to the more than 1 million people stranded by a surging river.